Candid Summaries on CBD Studies

Safety: Assessing the Safety of CBD in Healthy Dogs and Cats

KEY TAKEAWAYS:

  • This study brings to light the safety profile of CBD for both dogs and cats
  • CBD administration had no effect on food intake and body weight
  • No abnormal physical examinations, changes in behavior or organ dysfunction were detected after CBD administration in both dogs and cats
  • The administration of 4mg/kg of CBD daily to dogs and cats was well tolerated and not harmful 
  • CBD consumption by healthy dogs and cats did not alter blood analysis nor serum chemistry, supporting the secure and harmless profile of CBD 
  • Once again, this study provides foundation for the therapeutic use of CBD, since its properties have been vastly demonstrated and its safety evaluated
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Hemp Seed: a Vegan Source of Healthy Fat, Protein, Vitamins and Minerals

KEY TAKEAWAYS:

  • Polyunsaturated fatty acids (PUFAs) positively impact human and animal health in a variety of systems, including the cardiovascular and neurological
  • Essential fatty acids (EFAs) cannot be produced by animals and must be obtained through the diet
  • Linoleic and alpha-linoleic acid (omega 6 and 3, respectively) are essential to the well being and enhanced health of both humans and companion animals
  • This study concluded that hempseed oil has a content of over 80% in PUFAs and is exceptionally rich in omega 6 and 3
  • The ratio of omega 6 to 3 in hemp seeds is the optimal one and the one associated with little heart disease prevalence
  • The protein profile of hempseed oil is equally beneficial, containing some of the essential amino acids  
  • The study proved that the claimed healing and therapeutic properties of hempseed oil are supported by its nutritious profile 
  • Hempseed oil is an excellent source of nutrition and has been effectively demonstrated as an useful addition to animal diet 
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Safety: Evaluating the Safety of Escalating Doses of CBD in Healthy Dogs

KEY TAKEAWAYS:

  • CBD oil administration had little effect on food intake and physical activity 
  • There was no difference in the adverse effect profile of CBD oil when compared to its control group
  • Administration of CBD oil up to a dose of 62mg/kg per day resulted in mild side effects only and these side effects were also detected in the corresponding placebo group
  • No moderate or clinically significant adverse effects were reported after  administration of CBD oil up to 62mg/kg daily
  • The study provides novel data that separates the safety and tolerability of dose escalation of oil formulations predominant in CBD, THC, or CBD + THC (1.5:1) 
  • There was a clear distinction in the safety profile of the CBD oil when compared to THC or CBD+THC oil, with CBD oil being the most well tolerated
  • The study supports the safe and tolerable profile of CBD oil even when administered up to 62mg/kg daily, which is considered a much higher dose than would be anticipated for clinical use
  • Normally recommended doses range from 0.5 to 8mg/kg
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Hemp Seed: Beneficial Effect of Hempseed Against High Cholesterol

KEY TAKEAWAYS:

  • Hypercholesterolemia (HC) is the presence of high levels of cholesterol; it’s a major risk factor for cardiovascular diseases that, in turn, are the major cause of mortality
  • In dogs, high cholesterol levels are rather common and underdiagnosed; it is uncommon for it to lead to heart diseases, but it does put pets at risk for a series of negative conditions
  • Hypercholesterolemia in dogs may lead to: vomiting, diarrhea, abdominal pain and distention, decreased appetite, anorexia, pancreatitis, fat deposit on the cornea or eye (which in turn lead to white patches on the surface of the eye, inflammation or even blindness), skin abnormalities (itching and hair loss) and seizure activity
  • In cats, HC can cause cutaneous lesions and peripheral neuropathies (nerve disease)
  • Hempseed is abundant in healthy fatty acids, proteins, fiber, vitamins and has an optimal ratio of omega 6:omega 3
  • The study put into evidence the antioxidant capacity of hempseed
  • The hempseed diet was able to decrease the levels of cholesterol, LDL and triglycerides and increase the HDL levels
  • In regard to the ameliorative effect of hempseed on hypercholesterolemia, the hempseed diet was able to reduce the aorta thickness (cause by a high fat diet), indicating that hempseed administration prevents the development of atherosclerotic changes as indicated by lesser intimal damage, lipid deposition, and and lesion surface area
  • Finally, hempseed demonstrated protection from certain pathological indicators of cardiovascular insults that were present in rats that were fed a high-fat diet
  • The anti-hypercholesterolemic, antioxidant and anti-inflammatory properties of hempseed were well documented in the current study and it therefore proposes the therapeutic potential of hemp in HC-associated diseases
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